The investigators also identified medicines withdrawn for safety factors from the FDA website and from a 2005 report by the FDA’s Center for Medication Evaluation and Study. The FDA approved 748 new drugs between 1975 and 2009, the new study found, and about 15 % of these newly-approved drugs received one or more black-box warnings. About 4 % of the drugs were withdrawn from the marketplace due to safety concerns. Overall, the researchers found 208 events of withdrawal. Since the Act arrived to effect, median drug acceptance times were slice in half – – from 33.six months in 1979-1986 to 16.1 months in 1997-2002, the investigators wrote. Nevertheless, between 1999 and 2009, outpatient prescribers wrote 30 million prescriptions for each of nine drugs which were afterwards withdrawn for safety factors or that received black-box warnings because of their potentially deadly side effects.‘The power of virally infected cells to spread so quickly from the website of infection to varied lymph nodes throughout the body was unexpected,’ Dr. Sodora said. Researchers further examined the route by which cells carried SIV through the entire bodies of infected monkeys and discovered that T-cells and macrophages likely played key roles in disseminating the virus. Because SIV spreads therefore rapidly throughout the bodies of infected monkeys, it may help clarify why antiviral therapies can efficiently protect a monkey or HIV illness of humans only if they are given within hours of exposure to the virus.