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Neither of the parties endorse or suggest any commercial products, services, or equipment.. Persistent pain common in affective disorders By Eleanor McDermid, Senior medwireNews Reporter Individuals with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, analysis shows. However the frequency of pain at two to three sites rose from 13.2 percent of the 116,184 people without a mood disorder, to 19.8 percent of the 31,814 people who have MDD and 22.6 percent of the 1613 people who have bipolar disorder.8 percent, 4.5 percent and 5.8 percent of the groups, and widespread pain by 0.8 percent, 1.9 percent and 3.3 percent, the united team reports in BMC Psychiatry. After accounting for confounders including chronic comorbidities, the likelihood of having a disposition disorder was considerably increased in people with chronic pain, weighed against no pain, and the relative risk ratio improved with the number of affected sites.