Results of this research, along with an accompanying editorial, were released in the current issue of the journal Molecular Cell. The findings will be of interest to scientists who are developing new-generation drugs that target cancer at the molecular level, regarding to John Sedivy, principal investigator of the scholarly research and a professor in the Division of Molecular Biology, Cell Biology and Biochemistry. Every time chromosomes reproduce, telomeres obtain shorter. As telomeres dwindle, cell division altogether stops. Senescent cells do not function the real way young cells do, and so are believed to become associated with skin wrinkles, disease fighting capability problems and age-related illnesses, including cancer. A proteins called p21 acts as the molecular change that triggers telomere-initiated senescence.Also frozen was a well planned review in September of 22 applications totaling $54 million. NIH director Francis Collins welcomed Thursday’s purchase, however the NIH didn’t say specifically what would eventually the applications. Proponents of the research say it could lead to treatments for major diseases because the cells have a distinctive ability to develop into different types of tissue and is ethical since it uses discarded embryos. Foes state the research is much less promising than adult stem-cell research and morally objectionable since it destroys embryos . The Boston Globe: For scientists and patient advocacy groups who applauded President Obama’s decision to increase federal funding for stem cell analysis last year, the new decision was welcome news.